Stem cells

This study aimed to investigate the ability of mesenchymal stem cells derived from bone marrow of human and rat to transdifferentiate into functional neural like cells. A study was made on two different models (human and rat) using two different techniques (direct plating, and density gradient method) respectively. Immunophenotypic analysis demonstrated that human and rat BM-MSCs at passage three uniformly positive for CD44 sub-population. However, MSCs were always found to be negative for heamatopoietic specific markers CD34. To explore the possibility of BM-MSCs in vitro transdifferentiation, the expanded MSCs from third passage were allowed to reach 80% confluence and induced to differentiate into neuron like cells by an enhanced three-step protocol. The identity of the NLCs were illustrated by the analysis of morphology using immunocytochemistry.

Цена: 5097.00 RUR

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Stem cells

Cell is the structural and functional unit of life. A living cell is a true representative of life with its own organisation and specialised functions. Scientists have been interested in cell biology since the advent of microscopes in 18th century. Stem cells are defined as clonogenic, unspecialised cells capable of both self renewal for long periods and multilineage differentiation contributing to regenerate specific tissues. They can theoretically divide without limit to replenish other cells as long as the person is still alive. Research on stem cells and their application to treat various diseases is still at a preliminary stage. However, results from animal models are very promising and many researchers believe that it is only a matter of time before the same results can be achieved with human stem cell.

Цена: 4631.00 RUR

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