Radiobiology in Prostate Cancer Treatment

Cancer is becoming one of the most devastating diseases in the world. Reports from the International Agency for Research on Cancer predict that the global cancer rates will increase 50 percent by 2020. In western countries prostate cancer is the most common cancer in males. To reduce the suffering and death due to cancer is now one of the biggest challenges ever. About 60% of cancer patients receive radiotherapy as part of their disease management. Three dimensional conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) are being used successfully for both the palliative and curative treatments of cancer. The main aim of curative radiotherapy is to deliver a dose of radiation that is high enough to destroy the tumor cells while at the same time minimizing the damage to normal healthy tissues. Radiobiological parameters are used to evaluate and predict the outcome of a treatment plan. In this book, 3D-CRT and IMRT treatment plans for a prostate cancer patient are compared by using a radiobiological model.

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