Colorectal Cancer (CRC) sites among 5 top cancers in Kashmir (North India) owing to peculiar dietary habits and life style. In this book author has tried to summarize colorectal cancer and its etio-pathology. Author has studied various genes and their relationship with the development of CRC. Significant role of reduced expression of Axin in the development of CRC has been found and multistep model of CRC carcinogenesis has been supported in which alteration of DCC is late event and that of Axin an early event. Various genetic factors responsible for the development of colorectal cancer have been discussed. This book will be helpful for the students as well as researcher working in the field of cancer genetics interested in the study of CRC cancer.
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